b'Rainbow Diet News Forpeoplewhoactuallyhavetype-2Lifestyle Mattersdiabetes, another study showed that eat- A lifestyle program of a plant-based, ing flavonoid-rich foods can minimize thelow-carbohydrate, high-protein diet, with damage. A study offered men with type- supplemental probiotics, daily exercise, 2 diabetes a choice of plain hamburger orand stress management, can reverse DNA hamburger with a mix of the flavonoid-richchanges associated with aging and disease spices rosemary, garlic, ginger, black pep- risk. In other words, it can measurably re-per,andoregano.Thegroupeatingtheduce biological age. The DNA Methylation flavonoid-richspicehamburgerhadsig- (DNAm) Age Calculator, developed by nificantly better scores on measures of vas- Steve Horvath, Professor in Human Ge-cular function. Research has linked eatingnetics and Biostatistics at UCLA, is used Flavonoids are among the biochemicalflavonoid-rich foods with reduced risk ofto evaluate aging based on patterns of constituentsfoundinmanyplantfoodsotherillnesses,includingheartdisease,DNA methylation. According to naturo-thatgivethemtheircolors.Flavonoidscancer, and allergies. If you want to be surepathic doctor Kara Fitzgerald and associ-are also important antioxidants that helpyou have gotten all six kinds of the best- ates, the best biochemical markers of an defend our cells against the free radicalsknown flavonoids in a day, eat blueberries. individuals age are all based on patterns causedbyoxidativestress.AnexcessofXu H, Luo J, Huang J, et al., Flavonoids intake andof methylation. free radicals creates conditions where heartrisk of type 2 diabetes mellitus: A meta-analysis of disease, cancer, type-2 diabetes, and otherprospective cohort studies, Medicine 2018, 97(19): illnesses are more likely to occur. e0686, doi: 10.1097/MD.0000000000010686; Li Z, Ameta-analysisgroupedresultsofHenning S, Zhang Y, et al., Decrease of postpran-eight studies, covering more than 312,000dial endothelial dysfunction by spice mix added to high-fat hamburger meat in men with Type 2 diabetes volunteersoverperiodsfromfourto28mellitus, Diabetic Medicine 2013, 30(5): 590-595, years to assess the risk of developing type-2doi: 10.1111/dme.12120; Janabi A, Kamboh A, Saeed diabetes. The results showed that the risk ofM, et al., Flavonoid-rich foods (FRF): A promising developing type-2 diabetes dropped by 5%nutraceuticalapproachagainstlifespan-shorten-ing diseases, Iranian Journal of Basic Medical for each 300 mg per day increment of addedSciences2020,23(2):140153,doi:10.22038/consumption of flavonoid-rich foods.IJBMS.2019.35125.8353.Professional Skepticspital workers who are in direct contact Ameta-analysisbyresearchersatwith patients had not received a single NewMexicoStateUniversitythatre- dose of a COVID-19 vaccine by the end viewed 35 studies assessing vaccinationof May. The percentage was even higher, hesitancyinmorethan76,000health- around 33%, among workers in the na-careworkersaroundtheWorldfoundtions 50 largest hospitals.that about 25% of them were reluctant toResearchersatCarnegieMellonIn a study by Fitzgerald and colleagues get a COVID-19 shot. The main reasonsUniversity in Pittsburgh have investigat- on lifestyle changes, there was a 3.23-year cited were concerns about safety, effica- ed vaccine hesitancy by occupation, in andecrease in the DNAm Age of 38 men after cy, and potential side effects. Accordingongoing monthly survey of more than 1.9only eight weeks on the lifestyle program, toananalysisofdatacollectedbythemillionU.S.Facebookusers.Hesitancycomparedwith20meninthecontrol U.S. Department of Health and Humanamonghealthcareworkerscorrespondsgroup, who did not undertake any type of Services(HHS)from2,500hospitalsto income and education, ranging fromlifestyle change, which is a significant dif-across the United States, 25% of the hos- a low of 9% among pharmacists to highsference. In another study, at UCLA, a mod-of 20%-23% among nurs- est but significant reduction in DNAm Age ing aides and emergencywas found in individuals following a lean medical technicians. meat, fish, and plant-based diet. This study BiswasN,MustaphaT,also highlighted the benefits of a sensible KhubchandaniJ,etal.,diet, moderate alcohol consumption, and TheNatureandExtentphysical activity.ofCOVID-19VaccinationFitzgerald K, Hodges R, Hanes D, et al., Po-Hesitancy in Healthcare Work- tential reversal of epigenetic age using a diet and ers, Journal of Communitylifestyleintervention:apilotrandomizedclini-Health 2021, doi.org/10.1007/ caltrial,Aging2021,13(7):9419-9432,doi: s10900-021-00984-3;10.18632/aging.202913;QuachA,LevineM, CarnegieMellonUniversity,Tanaka T, et al., Epigenetic clock analysis of diet, RobinMejia,PhD,exercise, education, and lifestyle factors, Aging DirectoroftheStatis- 2017, 9(2): 419-446, doi: 10.18632/aging.101168; ticsandHumanRightsSteve Horvath, DNA Methylation (DNAm) Age Program and Special Faculty. Calculator at http://dnamage.genetics.ucla.edu/.H ealtHF reedomN ews /s ummer2021 11'